A shape-changing drug attacks tumors in several ways and improves outcomes in mice. A tumor is rarely made up of identical cells. As cancer progresses or adapts to treatment, different cells may display different molecular targets, allowing some to escape drugs designed to recognize only one. That diversity poses a challenge for antibody-drug conjugates, precision […]
Shape-Shifting Drug Supercharges Cancer Treatment in Mice
A shape-changing drug attacks tumors in several ways and improves outcomes in mice. A tumor is rarely made up of identical cells. As cancer progresses or adapts to treatment, different cells may display different molecular targets, allowing some to escape drugs designed to recognize only one. That diversity poses a challenge for antibody-drug conjugates, precision […]
Shape-Shifting Drug Supercharges Cancer Treatment in Mice
A shape-changing drug attacks tumors in several ways and improves outcomes in mice. A tumor is rarely made up of identical cells. As cancer progresses or adapts to treatment, different cells may display different molecular targets, allowing some to escape drugs designed to recognize only one. That diversity poses a challenge for antibody-drug conjugates, precision […]
Skin Damage May Begin Long Before You Can See It
Scientists have identified early signs of skin aging, finding that collagen’s internal structure begins to unravel before the fibers themselves break apart. Skin can appear structurally intact even as the collagen beneath it begins losing its internal organization. An international research team led by Hiroshima University has developed a method for detecting these early changes […]
Thousands of Years of Human History Unearthed in the Trent Valley
The exhibition reveals how prehistoric communities lived, adapted, and left traces across the Trent Valley. Beneath the Trent Valley, artifacts, pollen, animal remains, and layers of sediment preserve evidence of communities that lived there thousands of years ago. A new exhibition at the University of Nottingham Museum brings those discoveries together, revealing how archaeological research […]
Thousands of Years of Human History Unearthed in the Trent Valley
The exhibition reveals how prehistoric communities lived, adapted, and left traces across the Trent Valley. Beneath the Trent Valley, artifacts, pollen, animal remains, and layers of sediment preserve evidence of communities that lived there thousands of years ago. A new exhibition at the University of Nottingham Museum brings those discoveries together, revealing how archaeological research […]
Thousands of Years of Human History Unearthed in the Trent Valley
The exhibition reveals how prehistoric communities lived, adapted, and left traces across the Trent Valley. Beneath the Trent Valley, artifacts, pollen, animal remains, and layers of sediment preserve evidence of communities that lived there thousands of years ago. A new exhibition at the University of Nottingham Museum brings those discoveries together, revealing how archaeological research […]
30-Year-Old Museum Rock May Hide a New Mosasaur Species
Fossils newly identified in a rock collected 30 years ago in Osaka Prefecture may belong to a previously unknown species. For roughly 30 years, four mosasaur bones remained concealed inside a rock stored at the Natural History Museum, Kishiwada City. When researchers recently examined the unprepared specimen, they uncovered fossils unlike those of any mosasaur […]
Unzipping the Code of Life: Scientists Pinpoint Where DNA First Opens
Researchers mapped where DNA first opens and how a helicase gate may release one strand as genome copying begins. Before a cell can divide, it must open its tightly wound DNA and begin copying the entire genome. Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborating institutions have now traced this process to […]
Unzipping the Code of Life: Scientists Pinpoint Where DNA First Opens
Researchers mapped where DNA first opens and how a helicase gate may release one strand as genome copying begins. Before a cell can divide, it must open its tightly wound DNA and begin copying the entire genome. Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborating institutions have now traced this process to […]