Scientists have discovered distinct bacterial patterns in the saliva of patients with a deadly form of esophageal cancer. Bacteria living in the mouth may hold clues to a deadly form of esophageal cancer that often goes undetected until treatment options are limited. Researchers in South Africa have identified distinctive bacterial patterns in patients’ saliva, raising […]
Scientists Discover a Hidden Cholesterol Switch That Could Change How We Treat Heart Disease
Researchers uncovered how a high-cholesterol diet weakens the liver’s defenses and lowered LDL in mice by blocking the pathway, pointing to a potential new use for a shelved heart failure drug. A diet high in cholesterol can gradually weaken the liver’s ability to remove harmful cholesterol from the blood. Cholesterol-related heart disease remains the leading […]
A Major Drug Breakthrough Could Change How Ozempic and Wegovy Work
New compounds have overcome a longstanding challenge by directly targeting β-arrestins, proteins that regulate cellular signals, providing laboratory tools that could help guide more precise treatments with fewer side effects. A drug can hit its intended target and still have its effects cut short. That’s because cells have built-in molecular brakes that dial down signals […]
Researchers Find an Unexpected Benefit of Putting Sheep on Solar Farms
Solar grazing is helping sheep farmers expand their businesses, opening opportunities for rural jobs, new investment, and stronger agricultural supply chains. Sheep can feed on the vegetation growing around solar panels while farmers get paid to keep it under control. Too few sheep may leave farmers with grass they still need to mow, while heavier […]
Scientists Discover a New Butterfly Species Hiding in Plain Sight
Nearly identical butterflies share the same tropical forests, yet scientists still cannot fully explain how they recognize their own kind. When Andrés Orellana found caterpillars stripping the leaves from a Cecropia sapling in Venezuela, they had the familiar black bodies and yellow spines of Colobura butterflies. None, however, had the cream-colored markings seen in the […]
A Cave Full of Ancient Human Remains Has a Strange Secret: Where Are All the Males?
Ancient tooth proteins raise the possibility that Homo naledi, an extinct human relative, reserved a burial site for females, hinting at complex customs once thought unique to modern humans. For more than a decade, researchers have wondered why the adult fossils in South Africa’s Dinaledi Chamber look so much alike. The remains of Homo naledi, […]
Common Chemicals Trigger Alarming Changes in Human Breast Tissue Models
Chemicals that disrupt hormones may leave a molecular “scar” that could someday help identify people at higher risk of breast cancer, research in human breast tissue models suggests. People are typically exposed to several chemicals at once, including endocrine-disrupting chemicals that can interfere with the body’s hormones. Scientists have increasingly questioned whether these exposures contribute […]
A Deadly Virus Has Been Hiding in Brazil for 142 Years – and Scientists Just Uncovered a Hidden Danger
Scientists have uncovered new clues about the evolution of a rare, deadly Brazilian virus that has circulated largely undetected for more than a century. A rare and deadly virus went undetected in Brazil after genetic changes allowed it to escape existing laboratory tests. Scientists investigating two fatal infections have now identified the mutations responsible, developed […]
MIT Scientists Reprogram Immune Cells Inside the Body To Destroy Cancer
Natural killer cells reprogrammed inside mice eliminated lymphoma tumors and helped damaged livers heal, though whether this approach could help people with cancer or autoimmune disease remains unknown. To make a cancer treatment from a patient’s T cells, doctors first collect a blood sample and send it to a laboratory. There, these immune cells are […]
Scientists Discover Ancient Human DNA Hidden in Cave Walls for Thousands of Years
Ancient DNA from cave walls offers clues to prehistoric visitors’ sex and ancestry, potentially allowing scientists to investigate who used these spaces without disturbing archaeological deposits. A cave wall can hold traces of prehistoric visitors even when it has no paintings or other visible signs of human activity. Scientists have recovered ancient human DNA from […]